Programme

Overview: This session will explore what “good enough” means in modern radiotherapy, spanning technological uncertainties, clinical and radiobiological evidence generation and daily clinical practice. It will examine how advances in imaging, planning and treatment delivery may reduce some uncertainties while redistributing others, and why margins or probabilistic approaches in treatment planning will remain essential to ensure reliable dose delivery. It will highlight the importance of accurate and robust predictive models for “good enough” treatments and how patient-centred goals can guide safe, timely and meaningful care. Finally, the session will address the persistent gap between evidence, access and innovation.

Overview: This session explores how oncology research can be communicated effectively beyond academia, with a focus on patient-centred engagement. Through three complementary perspectives, it highlights the role of patient ambassadors, lived patient experience, and practical strategies for reaching non-specialist audiences. Speakers will discuss how to make complex science accessible, build meaningful connections with diverse communities, and foster dialogue rather than one-way dissemination. Emphasis is placed on translating research into real-world impact, inspiring trust, and ensuring that patient priorities shape research agendas. Designed for early-career researchers, the session offers both reflection and practical tools to strengthen communication and engagement.

Overview: This interdisciplinary symposium brings together clinical, technical, and research perspectives to examine the evolving role of CBCT‑-based dose calculations in adaptive radiotherapy (ART). It opens by outlining the key assumptions and uncertainties of CBCT‑-based dose computation and places them in context with the uncertainties already accepted in conventional planning. The session will then discuss three perspectives from different radiotherapy centres that have implemented, or are actively developing, CBCT-based recalculation workflows and CBCT-based adaptive planning. The first perspective reviews the transition from traditional TLP utilisation to CBCT‑-based dose assessment and examines how responsibilities are distributed within offline ART workflows. A head and neck workflow example illustrates how multidisciplinary roles (particularly RTT involvement) may evolve and where practical limitations remain. A second centre-based perspective introduces continuous, automated dose monitoring for patient specific quality assurance (PSQA). Using a lung dataset, it compares anatomical reporting with automated dose‑-based triggers, highlighting how numerical monitoring can reveal underreported changes and support scalable automation amid staffing pressures. The final presentation shares experience with trigger‑-based offline ART, discussing workflow development, patient‑-selection strategies, and the ongoing need for clearer criteria. Despite challenges, evidence shows that offline ART can deliver meaningful clinical benefit while underscoring the continued need for development in this area.

Overview: The choice of physical quantity for dose reporting in radiotherapy is crucial: it must correlate with clinical outcomes, be easily communicated to support consistent practice, and be accurately calculated or measured. Traditionally, dose to water fulfilled this role, as radiation doses were derived from measurements in water. However, modern dose calculation methods—such as Monte Carlo algorithms, linear Boltzmann solvers, and convolution/superposition techniques—now allow different dose definitions, creating uncertainty. This session will review recent recommendations clarifying these definitions, explain their historical context, discuss remaining challenges, and address quality assurance requirements for the reported dose quantity.

Overview: This joint ESTRO-ESMO session, chaired by Matthias Guckenberger, Giuseppe Curigliano and Barbara Jereczek-Fossa, will explore how radiation therapy and modern systemic treatments can be better integrated in precision oncology. International experts including Icro Meattini, Sean O'Cathail, Esmee Lauren Looman and Bharti Devnani will discuss SBRT-drug combinations, evidence generation, and innovative tools such as living systematic reviews and computational modelling. Together, these efforts are driving the future of multidisciplinary precision cancer care.

Overview: Brief background literature instigating the use of rectal preparation, rectal preparation methods, their effectiveness, and patient experience The patient group we stopped rectal preparation for, supporting patient information, documentation, and training Application of and results from a clinical audit of rectal volume and prostate motion without rectal preparation Development of and results from a patient’s experience preparing for prostate cancer radiotherapy survey. Discussion on stopping rectal preparation, personalising preparation, and clinical impact Background-Historical standards for immobilisation of head and neck cancer with a brief explainer of PTV expansions (Van Herk) and toxicities associated with head and neck RT Summary of Head and Neck Immobilisation-Literature Review Table Discussion of the OPEN Trial-this study was discussed at ESTRO plenary last year, however we now have full results which I can discuss. A discussion point from the OPEN Trial results-the potential for personalised margins through recognising patients who move less than the anticipated population based PTV expansion Discuss the feasibility study currently being run in SLRON exploring personalised margins A discussion of qualitative research I conducted with Head and Neck cancer patients on the open trial, highlighting the patient voice-need for shared decision making and how immobilisation and margins may be a time point where patients can be involved in treatment related decisions. Importance of respiratory motion reduction and overview of existing motion management techniques The Mechanically Assisted Non-Invasive Ventilation (MANIV) technique: Principles and implementations Clinical indications and contraindications IGRT image comparison: with and without MANIV Staff training and workflow adaptation Staff feedback and experience Patient experience and feedback Future developments and perspectives