Programme

Overview: This joint ESTRO-AAPM session will highlight emerging strategies for real-time intra-fraction adaptation and their potential to improve precision in radiation therapy delivery. Drawing on lessons from tracking-enabled platforms such as Vero, the session will explore how motion management has evolved from marker-based to marker-free approaches across moving targets including lung, liver, and pancreas. It will then address key enabling technologies, including real-time segmentation and quality assurance of auto-generated structures, as well as clinically available and emerging real-time tracking solutions, spanning geometry-guided and dose-guided approaches, advanced techniques to account for deformation, AI-based methods and quality assurance consideration. Finally, the session will discuss real-time dose reconstruction, covering adaptive dose calculation, dose accumulation across fractions, and the QA and validation challenges that must be addressed for safe clinical implementation.

Overview: The session provides a comprehensive overview of how vendor‑-provided technologies in radiotherapy can be safely introduced and maintained in clinical practice. It discusses key challenges and opportunities related to linear accelerators, treatment planning systems, patient‑-specific QA measurement solutions and AI‑-based tools. Attention is given to vendor‑-provided commissioning and pre‑-configured systems, the role of long‑-term QA data, and the need for independent and risk‑-based validation. By highlighting continuous quality improvement, sensitivity to clinical complexity and lifecycle management, the session illustrates practical approaches to safeguarding patient safety in increasingly automated radiotherapy workflows.

Overview: Synergy is defined as the concept where a combined effect of two or more entities is greater than the sum of their individual effects. Radiation oncology is evolving rapidly and on several fronts; where these fronts intersect, synergy can emerge. These joint evolutions carry the potential to have a lasting impact in the field, such as IGRT, which is now widely adopted. In this session, topics covered will range from combining protons with photons or MR-Linacs to pairing conventional RT with theranostics or FLASH, and adaptive RT with functional imaging. Five European experts in the field pitch their research, addressing potential clinical benefits, technical challenges, and future prospects.

Overview: Curious about biology-driven innovations in radiotherapy? Join this exciting session, where four expert speakers will pitch cutting-edge research areas. Topics include novel RT techniques such as FLASH, spatial fractionation, biology-guided radiotherapy, and boron-neutron capture therapy. Through exploration of recent results and the current status of each topic, the session will highlight potential clinical impact and reflect on how these emerging approaches may shape the future of radiotherapy.

Overview: This session explores the clinical impact of AI in radiotherapy workflows to date. Presentations will cover the use of AI in image segmentation and treatment planning, highlighting improvements in efficiency, consistency, and precision. In addition, the potential and current bottlenecks of AI in supporting clinical decision-making will be discussed. Finally, insights from the ARCHERY trial will demonstrate how large-scale evaluation can advance the global implementation of AI. Together, these talks provide a comprehensive overview of what AI has brought to clinical practice so far and what lies ahead.