Programme

Overview: Poster Discussions are presented in one of the sessions scheduled at the two poster discussion theatres. Each author will present a digital poster orally for 2 minutes, followed by 2 minutes for discussion. Sessions will be recorded and made available via the online platfrom and mobile app.

Overview: In this symposium, the latest advancements in Interventional Radio-Immunotherapy will be discussed, emphasizing the synergy between radiotherapy and immunotherapy to improve cancer treatment outcomes, with a special focus on brachytherapy (Interventional radiotherapy). The lectures will cover radiobiological aspects, including the effects of different radiation types and dose rates, and address challenges in dose distribution. Additionally, the symposium will focus on specific tumors such as gynecological, head, neck, skin, and urological cancers. Ongoing clinical trials and future directions will be explored, with an emphasis on personalized approaches based on tumor immune profiling to optimize treatment efficacy.

Overview: Over a decade ago, FLASH radiotherapy emerged in the field of radiation oncology with the promise of widening the therapeutic window. While the number of supporting preclinical studies has grown exponentially, technological and biological challenges have slowed its clinical translation, resulting in only a limited number of early-phase clinical trials currently underway. This panel discussion brings together three multidisciplinary experts with experience in clinical translation. They will explore why this promising technique has not yet been widely adopted in clinical practice and discuss the necessary steps and actions to ensure the safe and successful translation of FLASH radiotherapy into clinical use. The discussion will also highlight the importance of veterinary clinical trials and preclinical biology studies in bridging the gap from bench to bedside, ensuring that FLASH radiotherapy's potential is fully realized in both human and veterinary medicine.

Overview: This teaching lecture will focus on motion management strategies specifically when treating oligometastatic disease (OMD) in the thoracic and abdominal regions with SBRT. The lecture will be presented from the viewpoints of both the perspectives of the RTT and the medical physics expert (MPE). The MPE will start the lecture by giving a brief overview of the history of OMD. Concepts such as ITV, MidPos, MidVent and continuous target tracking will be discussed in the line of online adaptive delivery. The MPE will also pose a question over the optimal hardware for such treatment delivery- are ‘traditional’ linear accelerators sufficient or are dedicated, high technology units required? The RTT perspective will take the position of motion management when treating multiple volumes in the same plan on the MR-linac and will refer to the sites most commonly treated in this manner-lung, mediastinum, liver, abdominal volumes and abdominal lymph nodes. The presentation will follow the pathway from pre-treatment to on-treatment, leading to on-treatment decision making by the RTT with specific focus on what planes and which volumes to gate. Finally, some trouble shooting points will be given as well as consideration to questions which are still unanswered in this field.

Overview: This session explores innovative approaches to clinical research in radiation oncology, challenging traditional methodologies and highlighting the need for adaptability in a rapidly evolving field. The first talk discusses the limitations of RCTs, including their high costs, long timelines, and challenges in keeping pace with technological advancements. The second talk examines the role of real-world evidence, defining its scope, regulatory perspectives, and impact on clinical decision-making. The third talk explores pragmatic trials as a bridge between efficacy and real-world effectiveness, addressing their design and implementation. Finally, the session covers the Trials Within Cohort (TwiCs) approach, demonstrating how cohort-based randomised trials can offer ethical and practical advantages. Together, these talks offer a roadmap for modernizing clinical research in radiation oncology.