Coordinators:
Francesca Albertini, Switzerland
Rita Simões, United Kingdom
Pieter Populaire, Belgium
Scope
The Adaptive Task Force brings together a multidisciplinary group of medical physicists, radiation oncologists and radiation therapists from proton and photon centres across Europe. The task force operates transversally across all EPTN Working Parties (WPs) with the goal of preparing the field for clinical adaptive proton therapy (APT).
Objectives
- To standardise nomenclature for adaptive particle therapy (APT)
- To evaluate the clinical risk–benefit balance of APT
- To define multidisciplinary competencies and educational requirements for APT)
- To develop commissioning and quality assurance (QA) frameworks
- To assess cost-efficiency and resource implications
- To evaluate the impact on treatment margins and robustness
- To strengthen the connection between research and clinical practice
Publications
- Peer reviewed publications
Populaire Pieter, Simoes Rita, Nenoff Lena, Trnkova Petra, Placidi Lorenzo, Stützer Kristin, van Weerd Eva, Albertini Francesca. Terminology Proposal for Adaptive Particle Therapy Classification and Strategies. IJPT Feb 2026 (In press)
Lena Nenoff, Petra Trnková, Federica Bertini, Grete M. Engeseth, Per-Ivar Lønne, Silvia Molinelli, Hanna R. Mortensen, Andreia Maia Oliveira, Giovanni Pirrone, Lorenzo Placidi, Kristin Stützer, Juliette Thariat, Mirko Unipan, Eva van Weerd, Rita Simoes, Pieter Populaire, Francesca Albertini. 3281 SWOT Analysis of Online Adaptive Particle Therapy: Results from the EPTN adaptive task group. Radiotherapy and Oncology, Volume 206, Supplement 1, 2025, https://doi.org/10.1016/S0167-8140(25)01599-3
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Ongoing activities
1. Harmonization of online adaptive terminology
Leads: Pieter Populaire (BE), Francesca Albertini (SW), Rita Simões (UK)
Objective: Development of a unified and consistent terminology for adaptive proton therapy.
Manuscript accepted for publication at the International Journal of Particle Therapy in December 2025.
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2. SWOT Analysis for Online Adaptive Proton Therapy
Leads: Lena Nenoff (DE) & Petra Trnková (CZ)
Objective: To identify strength, weaknesses, opportunities and threats associated with APT.
The SWOT analysis was presented at ESTRO 2025 and manuscript is in revision.
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3. QA and Commissioning Recommendations
Leads: Lorenzo Placidi (IT) & Katarzyna Czerska (CH)
Objective: To define and provide guidelines on commissioning and QA requirements for adaptive proton therapy.
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4. Competence Matrix for Adaptive Workflows
Leads: Eva van Weerd (NL), Claudio Votta (IT), Rita Simões (UK)
Objective: To work towards establishing a robust RTT-led workflow model by identifying the competencies required for each workflow step and assigning the roles required for each competency.
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5. Imaging Guidelines for Adaptive Workflows
Leads: Lena Nenoff (DE), Pietro Pisciotta (NL), Petra Trnková (CZ) and Jenneke Jacobs (NL)
Objective: to identify the Minimum imaging quality requirements for APT, as well as QA approaches for corrected/synthetic images.
Upcoming Events
May 2026 in-person workshop TBD
Autumn 2026/Winter 2027 - Adaptive proton beam therapy course at PSI TBD
Past events
December 2025 (online) – Adaptive task force general meeting
September 2025 (in presence in London) – Launch of the task on requirements for APT
May 2025 (in presence at ESTRO 2025) - Workshop on QA and commission guidelines development (view agenda)
January 2025 (online) – General meeting (view minutes)
October 2024 (in presence meeting in Vienna during annual EPTN meeting) – workshop on SWOT analysis (view report)
June 2024 (online) – General meeting (view minutes)
April 2024 (online) – Task force kick off meeting (view minutes)
October 2023 (In presence meeting in Manchester during annual EPTN meeting) – 1st workshop Adaptive proton therapy, aimed at discussing the formation of the task force (view report)
Would like to get involved in the activities of the task force?
Please contact: eptn@estro.org