Programme

Overview: Adaptive radiotherapy (ART) has become more prevalent as planning and treatment systems advance, allowing for more efficient delivery of care across a wide variety of tumour sites. In order to further improve the quality and efficiency of ART, this symposium aims to provide insight from leading RTT and Physics experts working across different adaptive systems. Topics covered will range from process improvement initiatives, training and credentialing frameworks, the integration of AI and how proton therapy is using adaptive workflows. This symposium will be of great interest to current and future users of adaptive systems.

Overview: Proffered Papers are presented in one of the sessions scheduled in the main session halls. Each author will present orally for 7 minutes, followed by 3 minutes for discussion. Sessions will be recorded and available on-demand.

Overview: In radiation oncology, treatment decisions require balancing therapeutic efficacy with the risk of toxicity. Normal Tissue Complication Probability (NTCP) models offer a quantitative framework for estimating treatment-related side effects, potentially enabling safer, more personalized care. However, whether they should take the lead in clinical decision-making remains a matter of debate. Arguing for the motion, Markus Alber and Hans Langendijk will advocate for NTCP models as essential tools for guiding patient management. Opposing them, Tiziana Rancati and Ivan Vogelius will highlight model limitations and question their reliability. The stage is set for a compelling debate—but who has the stronger arguments? That’s for you, the audience, to decide!

Overview: Mini-Orals are presented at one of the sessions scheduled in the two mini-oral theatres. Each author will present a 4-slide PowerPoint orally for 4 minutes, followed by 3 minutes for discussion. Sessions will be recorded and made available via the online platform and mobile app.

Overview: This session explores innovative approaches to clinical research in radiation oncology, challenging traditional methodologies and highlighting the need for adaptability in a rapidly evolving field. The first talk discusses the limitations of RCTs, including their high costs, long timelines, and challenges in keeping pace with technological advancements. The second talk examines the role of real-world evidence, defining its scope, regulatory perspectives, and impact on clinical decision-making. The third talk explores pragmatic trials as a bridge between efficacy and real-world effectiveness, addressing their design and implementation. Finally, the session covers the Trials Within Cohort (TwiCs) approach, demonstrating how cohort-based randomised trials can offer ethical and practical advantages. Together, these talks offer a roadmap for modernizing clinical research in radiation oncology.