Copenhagen, Denmark
Onsite/Online

ESTRO 2022

Session Item

Breast
6006
Poster (digital)
Clinical
Using CPAP to decrease the cardiac dose in the radiotherapy of the left-sided breast cancer
Ahmed Gawish, Germany
PO-1182

Abstract

Using CPAP to decrease the cardiac dose in the radiotherapy of the left-sided breast cancer
Authors:

Ahmed Gawish1, Mathias Walke1, Burkard Röllich1, Thomas B. Brunner1

1Medical Faculty University Hospital Magdeburg, University Clinic for Radiation Therapy, Magdeburg, Germany

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Purpose or Objective

 Reducing the heart dose in left-sided breast cancer radiotherapy is very crucial. We sought to research the impact of using CPAP (continuous positive airway pressure) to minimize heart dose in breast cancer radiotherapy

Material and Methods

 Patients with left breast cancer receiving adjuvant radiotherapy were enrolled on this study using CPAP to minimize the heart dose for radiotherapy. Every patient was planned and simulated with and without CPAP, and the best dosimetric results provided the patient's treatment, respectively. Besides, information or data on the differences in heart and lung volume and position and boost cavity position with and without CPAP was well analyzed.

Results

Only fifteen patients were available for treatment. The median age was 60 years, all were treated to regional nodes and breast with 50 Gy. The mean lung volume present with CPAP was 30% greater than without CPAP (3370 cc vs. 2600 cc) and this increase the distance between the heart and the wall of the thorax from mean 2,7 cm (2,4-2,9) to  mean 4,17 cm (3,8- 4,9).V20 of the lungs decreased from 14,8 to 11,43 with CPAP, and CPAP decreased median D2 heart dose from 14,4 to 10,4 Gy, regarding the DVH and the Dmean to LAD decreased too from 15,4 to 10,6. Remarked increase of the heart volume under CPAP, mean difference in heart volume is 83cc (40cc-153cc).

Conclusion

The CPAP helped the radiotherapy process and resulted in excellent treatment for left-sided breast cancer. This technique is worth further investigation or study to normal tissue sparing treatment of left-sided breast cancer patients.