Session Item

Treatment planning: applications
Digital Poster
Physics
Procedure for total body irradiation (TBI) with Helical Tomotherapy
Carlos Ferrer, Spain
PO-1876

Abstract

Procedure for total body irradiation (TBI) with Helical Tomotherapy
Authors:

Carlos Ferrer1, Concepción Huertas1, Rodrigo Plaza1, Patricia de la Monja1, Cristina Mínguez1, David García1, Alejandro Aznar1, Moisés Sáez1

1H.U. La Paz, Medical Physics Department, Madrid, Spain

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Purpose or Objective

The procedure for performing a total body irradiation (TBI) treatment in a tomotherapy unit is described.

Material and Methods

Three TBI treatments were performed with TomoHDâ„¢ tomotherapy equipment. The immobilization consists of two indexed moldcare couches and a thermoplastic  mask. Due to limitations in the movement of the table the whole body image is acquired in two series, a head gantry CT and a feet to gantry CT. In addition, a 4D CT is performed to contour the lungs. All with a slice thickness of 5mm. In both series, the target volume is the external contour of the patient, expanded by 5 mm to ensure that the skin receives the prescribed dose (Dp). It is contoured to the overlapping area of both plans, where 5 gradient volumes of 2 cm thickness are generated. Between successive gradient volumes the dose is reduced by 2 Gy, so that positioning errors do not lead to large dose variations. In the region prior to the gradient, an overdosage is generated by adding up the plans. To avoid this, 2 to 4 cm of the patient's contour are prescribed at 95% Dp. The lungs are delimited on the MIP image and reduced by 1 cm in all directions allowing a gradient zone from the costal wall, which is also contoured to verify that it is not underdosed.

The treatment schedule is 12 Gy in 6 fractions, twice a day, separated by more than 6 hours. The treatment goals are at least 95% volume coverage at 95% Dp , dose as homogeneous as possible and maximum lung dose of 10 Gy and minimum of 7 Gy. The length of both upper and lower plans should be less than 120-126cm due to limitations of table movement and immobilization indexations.  The parameters of the upper plan are: field width=5 cm, pitch=0.287, modulation factor=2 till 3. The parameters of the lower plan are: field width=5cm, pitch=4, modulation factor=2.

 

Both plans are verified with ArcCheck, the gamma criterion (3 %, 3 mm) is applied. The overlap region is verified with both ArcCheck and radiochromic, both plans are irradiated consecutively by rotating the equipment. During treatment, radiochromic film strips are placed in the overlap region and in regions where repositioning is less reproducible.

Results

Coverage is greater than 98% of the external contour at 95% Dp. The lungs have a minimum dose of 7.1 Gy, mean of 7.5 Gy and maximum of 9.1 Gy. The average treatment time is 45min of irradiation and 14min of imaging.

In the verification of the plans 98% of the points pass the gamma criterion. In the measurements in the gradient zone the dose variations are less than 2.5%.

Conclusion

The treatment of TBI with tomotherapy allows the treatment to be performed with the patient in a comfortable position and with accurate positioning verification using the equipment's own imaging system.