Marianne Koritzinsky

Canada

Biography

Dr. Koritzinsky has a PhD from the University of Oslo (Norway) and completed postdoctoral training at the University of Maastricht (The Netherlands). Dr. Koritzinsky is now a Senior Scientist at the Princess Margaret Cancer Centre in Toronto (Canada) where she co-leads the Tumor Microenvironment Program. She is Associate Professor and Director of Research at the Department of Radiation Oncology, with cross appointments to the Department of Medical Biophysics and the Institute of Medical Science, University of Toronto. Research in Dr. Koritzinsky's laboratory is focused on vulnerabilities in cancer that emerge as a consequence of the tumor microenvironment. The tumor microenvironment is characterized by low oxygen availability (hypoxia), metabolic reprograming and redox imbalances that stimulate a more aggressive cancer phenotype, resistance to radiation-, chemo- and immune-therapy, and ultimately poor patient prognosis. The aim of Dr. Koritzinsky’s research program is to increase our understanding of molecular and cellular responses to hypoxia, altered metabolism and redox homeostasis, with the ultimate goal of targeting these responses to improve patient outcomes. Dr. Koritzinsky is a recipient of the ESTRO-Juliana Denekamp research award, the Terry Fox Research Institute New Investigator award, the Radiation Research Society Michael Fry award, the Department of Radiation Oncology Excellence in Research Leadership Award and the Medical Biophysics Student Association Teaching award.